Tag: Amsterdam

  • Can blood NAD+ level reveal your biological age?

    When we think about aging, we often focus on visible signs like wrinkles, gray hair, and decreased energy. However, we are now looking deeper, exploring the molecular changes that occur as we age. Among these, NAD+ (nicotinamide adenine dinucleotide) plays a crucial role. This important molecule is at the heart of the NADIS consortium’s research,…

  • Everybody Wants to Live Forever, but Nobody Wants to Grow Old

    One day, you might need help going to the bathroom, be unable to tie your own shoes, and struggle to follow a simple conversation. In other words, lose your autonomy and become dependent on other people to take care of you. Notably, this only happens to the lucky ones. The late stages of aging are…

  • Maria’s secondment

    During my secondment in the Laboratory of Systems Biology and Genetics at EPFL, I had the unique opportunity to conduct an experiment involving the treatment of murine cells from subcutaneous tissue with NAD+ precursors and a PARP1 inhibitor. The process was highly interesting to me and included: the extraction of the stromal-vascular fraction, FACS sorting…

  • Thomas’ secondment

    During this secondment, with the assistance of the NADIS Ph.D. student and theanalysts of the lab, I analyzed different adipocyte samples using the mass spectrometry. This includes 3D adipocyte spheroids and white adipose tissue samples. I have learned how to prepare samples for the mass spectrometry analysis and how to interpret the results obtained from…

  • Introduction

    The life of a PhD candidate can be challenging, especially as an international fellow. You arrive in a completely new place with hope for the best and readiness to face the worst, uncertain about the future. Adjusting to a new reality and interacting with people from diverse backgrounds, speaking different languages, presents its own set…

  • Benelux Metabolomics Days 2023

    Just last week, NADIS doctoral candidate Maria M. Tretowicz from Amsterdam UMC presented groundbreaking research on whole-blood nicotinamide adenine dinucleotide (NAD⁺) measurements at the Benelux Metabolomics Days 2023. Collaborating with the Amsterdam Movement Sciences Institute and the Amsterdam Cardiovascular Sciences Institute, her presentation included a single cohort study encompassing diverse groups: young and old individuals,…

  • Name:  Riekelt Houtkooper  Nationality:  Dutch  MSc education:  Biomedical Sciences, University of Amsterdam  PhD education:  Laboratory Genetic Metabolic Diseases, University of Amsterdam  Postdoc education:  Laboratory for Integrative and Systems Physiology; Ecole Polytechnique Federale de Lausanne  Current position:  Professor of Translational Metabolism, Amsterdam University Medical Centers, University of Amsterdam  DCs:  Maria Tretowicz, Kasper Vinten, Melisa Ermert  Social…

  • DC8

    Name:  Melisa Emel Ermert  Nationality:  Turkish  MSc education:  Molecular Biology of the Cell Current position:  PhD Candidate Supervisors:  Prof. Dr. Riekelt Houtkooper, Dr. Herma Renkema, Prof. Dr. Eija Pirinen   Social media handles:  LinkedIn Description of the project:  Within the scope of my research project, the therapeutic role of NAD+ precursors and Khondrion’s compounds, particularly focusing…

  • DC2

    Name:  Kasper Tore Vinten Nationality:  Danish  MSc education:  Pharmaceutical Sciences  Current position:  PhD Candidate at Amsterdam UMC  Supervisors:  Prof. Dr. Riekelt Houtkooper, Dr. Georges Janssens, Dr. Rubén Zapata-Pérez  Social media handles:  LinkedIn  Description of the project: The focus of the present project is reduced NAD+ precursors in a translational setting. This encompasses two main aspects:…

  • DC1

    Name:  Maria Magdalena Trętowicz  Nationality:  Polish  MSc education:  Chemistry and Forensic Toxicology  Current position:  PhD Candidate at Amsterdam UMC  Supervisors:  Prof. Dr. Riekelt Houtkooper, Dr. Georges Janssens  Social media handles:  LinkedIn Description of the project: As a member of NADIS, I am committed to creating an advanced mass spectrometry framework that supports the research efforts…