Author: Admin
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NAD Metabolism and Signaling FASEB Conference in Lisbon (2)
Last month, our DC Thomas attended the FASEB Conference – NAD Metabolism and Signaling in Lisbon, Portugal, from August 25th to 29th. This event brought together leading experts and researchers to discuss the latest findings and advancements in NAD metabolism. During the conference, Thomas presented a poster titled: “Fluxomics Analysis of NAD Metabolites in Human…
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NAD Metabolism and Signaling FASEB Conference in Lisbon
Raúl Pérez Mato, NADIS doctoral candidate at the University of Genova, shared his work at the NAD Metabolism and Signaling FASEB Conference in Lisbon. With a poster presentation called “The TRPM2 ion channel regulates the browning process in human adipose tissue” he showed his latest results from this project that studies TRPM2, a calcium channel…
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Everybody Wants to Live Forever, but Nobody Wants to Grow Old
One day, you might need help going to the bathroom, be unable to tie your own shoes, and struggle to follow a simple conversation. In other words, lose your autonomy and become dependent on other people to take care of you. Notably, this only happens to the lucky ones. The late stages of aging are…
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NAD⁺ precursor supplementation – Beware of pharmaceutical companies
In the goal of improving our daily health, we tend to remember our doctor’s usual recommendations: a healthy diet, physical activity, 7-8 hours of sleep per night, no smoking, limiting alcohol consumption, etc. Yet, according to influencers (Egle Pavyde, 2024), journalists (David Cox, 2024; Emily Dougherty, 2024), and YouTubers (Rhonda Patrick, 2020), there is a…
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Paper summary
The scientific study entitled “Nicotinamide riboside first alleviates symptoms but later downregulates dopamine metabolism in proteasome inhibition mouse model of Parkinson’s disease,” published in Heliyon, provides a comprehensive examination of the effects of nicotinamide riboside (NR) on Caenorhabditis elegans and mouse models for Parkinson’s disease (PD). The study emphasizes the initial therapeutic benefits of NR,…
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Are NAD⁺ Precursors Needed at All?
In recent years, there has been a noticeable rise in health consciousness, especially among younger generations. This demographic is increasingly interested in aging and how to slow or even reverse it. Social media platforms like YouTube are showing a trend in anti-aging channels and biohackers sharing their strategies to maintain youthfulness. This surge in interest…
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Maria’s secondment
During my secondment in the Laboratory of Systems Biology and Genetics at EPFL, I had the unique opportunity to conduct an experiment involving the treatment of murine cells from subcutaneous tissue with NAD+ precursors and a PARP1 inhibitor. The process was highly interesting to me and included: the extraction of the stromal-vascular fraction, FACS sorting…
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NAD+ and obesity
Obesity, a complex chronic disease characterized by the excessive accumulation of fat, represents one of the major challenges for public health worldwide. In the year 2022, 1/8 of the world population was affected by it. Obesity significantly increases the risk of suffering from type 2 diabetes, cardiovascular diseases, or even certain types of cancer. In…
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Unlocking Youthful Vitality
NAD+-Powered Diet and Lifestyle Tips for Aging Gracefully Are you looking to boost your energy levels, improve cognitive function, and enhance your overall well-being naturally? The key could lie in increasing the levels of NAD+ (Nicotinamide Adenine Dinucleotide) in your body. Previously, we discussed the biochemical pathways and foundational aspects of NAD+ in anti-aging. Now,…
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Thomas’ secondment
During this secondment, with the assistance of the NADIS Ph.D. student and theanalysts of the lab, I analyzed different adipocyte samples using the mass spectrometry. This includes 3D adipocyte spheroids and white adipose tissue samples. I have learned how to prepare samples for the mass spectrometry analysis and how to interpret the results obtained from…